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The 5 Best Weed Killers (2022 Review)

An effective herbicide can get rid of a variety of weeds that have invaded your lawn. In this review, the This Old House Reviews Team researched the five best weed killers on Amazon to help you find the product that’s right for you. The products included in this article are available at various home improvement stores, local home centers, and online retailers like Amazon.

Weed Killer Courtesy Amazon

Whether they appear on your lawn, patio, garden, or fence, weeds are an annoyance for any homeowner. Thankfully, there are many easy-to-use and effective weed killers to help remove these unwanted plants. To help you select the weed killer that’s right for you, the This Old House Reviews Team researched the best weed killers on Amazon. Here are our top five recommendations.

Top 5 Weed Killers


Best For Gravel: RM43 43% Glyphosate Plus Weed Preventer

This weed killer contains 43% glyphosate. This ingredient kills any plants it comes into contact with, so it works best for weeds on pavement or gravel. With one gallon of concentrated liquid for over 17,000 square feet, this product will protect a large area.

Key Features

  • Comes in a one-gallon bottle of concentrate
  • Treats 17,297 square feet for up to a year
  • Rainproof within two hours
  • Kills weeds
  • Works on surfaces without vegetation

What Customers Are Saying

Those who left positive reviews said that this weed killer worked well on large areas and was simple to use. However, dissatisfied customers said that it took too long to kick in or that it was as effective as cheaper, generic brands.


Most Customizable: Spectracide Weed & Grass Killer

This concentrated weed killer produces visual results within three hours of application on driveways, fences, flower beds, shrubs, and other surfaces. With multiple size and quantity options, your purchase can be customized to meet the specific needs of your yard.

Key Features

  • Comes in a 64-ounce bottle of concentrate
  • Available in other bottle sizes and quantities
  • Rainproof after 15 minutes
  • Shows results in as little as three hours
  • Kills weeds and grasses
  • Works on driveways, walkways, fences, trees, flower beds, shrubs, and more

What Customers Are Saying

Happy customers said that this product was long-lasting, fast-working, and persistent with tough weeds. However, other reviewers claimed that it caused damage to lawns and that it didn’t work as advertised.


Best For Multiple Weed Types: Roundup All-in-One Weed Killer For Lawns

With the ability to kill over 250 types of weeds, including crabgrass, dandelions, and clovers, this weed killer eliminates almost every type of plant pest in your garden. This weed killer doesn’t damage lawns either, allowing you to spray it directly on grass or flower beds.

Key Features

  • Comes in a 1.33-gallon spray bottle
  • Available in ready-to-spray and concentrate bottles
  • Rainproof in as little as three hours
  • Kills Northern grasses

What Customers Are Saying

Those who liked this weed killer said that it was easy to spread and killed multiple types of plants with a minimal amount of spray. Dissatisfied customers didn’t like that it contained toxic ingredients.


Best For Flower Beds: Ortho GroundClear Weed & Grass Killer

With visible results in just 15 minutes, this weed killer can eliminate unwanted plants from your flower bed or garden in a snap. This spray starts working immediately on all types of weeds and grasses.

Key Features

  • Comes in a one-gallon spray bottle
  • Rainproof within two hours
  • Shows results in 15 minutes
  • Kills weeds and grasses
  • Works on hardscapes, landscape beds, and vegetable gardens

What Customers Are Saying

Satisfied customers said that this weed killer worked quickly, didn’t kill wanted plants, and featured a simple-to-operate nozzle and wand. However, other customers said that it didn’t eliminate all of their weeds even after going through the entire bottle.


Best Vinegar Weed Killer: Green Gobbler Weed & Grass Killer

Without using harsh chemicals or glyphosate, this product is effective on surfaces ranging from sidewalks to flower beds. It provides visual results within 24 hours with its pet-friendly and non-toxic formula.

Key Features

  • Comes in a one-gallon spray bottle
  • Shows results within 24 hours
  • Kills crabgrass, dandelions, clovers, and more
  • Works on mulch beds, sidewalks, driveways, flower beds, and more

What Customers Are Saying

Customers who left positive reviews liked that this product was inexpensive and safe for families with children and pets. Dissatisfied customers said that it left an unpleasant smell and caused damage to wood surfaces.


Buyer’s Guide

Not all weed killers work well for every surface or weed. Here are several factors to consider when determining which weed killer is best for your lawn.

Type

Different types of weed killers are recommended for different types of plants and areas of application. Here are some common types of weed killers to look out for.

Contact

This type of weed killer kills plants as soon as it makes contact with them. Contact weed killers don’t attack the root system, but they weaken weeds after multiple uses. This type of weed killer is effective for annual weeds that consistently reappear.

Systemic

Systemic weed killers are applied directly to the foliage of a plant. They take several weeks to start working, but they fight the plant’s internal root system. This type of weed killer is good for plants that are difficult to kill, such as dandelions and poison ivy.

Residual

These weed killers poison soil, killing all plants within the treated area. They can be long-lasting, so it’s best to avoid using this type of weed killer in areas that contain edible plants.

Emergence

Emergence refers to how far along in the weed’s growth cycle that weed killer needs to be applied. Some weed killers are pre-emergent, meaning they should be applied to prevent weeds from growing. Post-emergent weed killers are used for weeds that have already sprouted. They kill the plant while also ensuring it doesn’t grow back.

Selectivity

If you’re using a weed killer on flower beds or gardens, it’s critical to look for selective weed killers, as they avoid beneficial plants and solely target weeds. Meanwhile, non-selective weed killers destroy all plants in the vicinity.

Frequently Asked Questions

How do weed killers work?

Generally, weed killers are herbicides that interfere with weed growth by either destroying their root formation or restricting the growth and development of their cells, causing them to eventually die.

Are weed killers dangerous around pets?

It depends on the weed killer. Some aren’t safe for households with pets, while others are safe once they’re dry. The safest option is a weed killer with an organic formula.

How long does it take for weed killers to work?

Typical weed killers will take anywhere from two to six weeks to fully kill the root of a plant. Certain types of herbicides will produce faster results, but these herbicides kill the flowering part of the plant and not its root system.

Why Trust The This Old House Reviews Team

This Old House has empowered homeowners for more than four decades with top-notch home improvement content in the form of television programs, print media, and digital content on its website and social media platforms. The This Old House Reviews Team focuses on creating in-depth product and service review content to help inform your purchasing decision for just about any item or resource that you might need for your home. The This Old House Reviews Team has written over 1,000 reviews on products in the home space, from cordless drills to kitchen trash cans, lawn mowers, and dining room decorations.

We recommend products in each review using an intensive research process, spending hours combing through the best available models on Amazon. For a product to make our list of top picks, it must hold a solid sales record on Amazon, have consistently positive customer reviews, and offer unique features, among other factors. After narrowing down our list of recommendations, we conduct additional research and sometimes in-person testing to ensure that the products meet our standards. Once we conclude the research phase, we craft a well-rounded, user-friendly article that includes our recommended products and additional information to help homeowners like you make the right purchase.

To share feedback or ask a question about this article, send a note to our Reviews Team at reviews@thisoldhousereviews.com.