That doesn't mean "ready for cleanup." While some new paints dry to the touch in as little as an hour, many manufacturers recommend waiting 2 to 8 hours, depending on temperature and humidity, before applying a second coat. But even after paint is dry, it still needs to cure. (Curing is the chemical process by which the paint bonds to the surface.) Recommended cure time can be anywhere from two days to four weeks, depending on the maker; check online or ask a salesperson for the info. After that period, walls and trim are safe to wash or scrub.